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Monday, 11 March 2013

Red wine drug 'could help us live to 150'

The drugs are synthetic versions of resveratrol, found in red wine, an organic chemical believed to have an anti-ageing effect, by boosting activity of a protein called SIRT1.

GSK, the pharmaceutical firm, is testing them on people with particular medical conditions, namely Type II diabetes and psoriasis, a serious skin condition.

David Sinclair, professor of genetics at Harvard University, said ageing might not actually be an "irreversible affliction".

He said: “Now we are looking at whether there are benefits for those who are already healthy.

"Things there are also looking promising. We're finding that ageing isn't the irreversible affliction that we thought it was.

"Some of us could live to 150, but we won't get there without more research."

He explained that increasing SIRT1 activity improved how well our cells operated, making them less sluggish. In previous experiments, mice, bees and flies given the SIRT1-boosting compounds lived longer.

Writing in the journal Science, Prof Sinclair claimed to have performed experiments which showed these resveratrol-based compounds were having a direct effect on health. Some scientists have argued that the effect was not real, but experimental artifice.

Despite the controversy, there have already been promising results in some trials with implications for cancer, cardiovascular disease and heart failure, Type II diabetes, Alzheimer's, Parkinson's, fatty liver disease, cataracts, osteoporosis, muscle wasting, sleep disorders and inflammatory diseases such as psoriasis, arthritis and colitis.

Current trials look at how the compounds might help treat these age-related disease.

But Prof Sinclair believed that in time they would also be examined for their preventative effect. Just as statins are used today to prevent heart disease and strokes, so these compounds could be used to slow a wide-range of diseases.

Prof Sinclair is a consultant and inventor on patents licensed to Sirtris, the GSK company running the trials.


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Retired urged to 'face up to old age'

Unwillingness to face up to getting older threatens to condemn the newly retired to spend their final years in isolation or institutions, a coalition of experts led by a former care services minister warns today.

The belief that people should be “young forever” has created a taboo around ageing that could turn elderly people in the future into “passive victims”, unable to make a choice about where they live, they said in a letter to The Daily Telegraph.

The group, which includes Paul Burstow, a former care services minister, and Baroness Greengross, is calling for more openness among those approaching old age to the idea of taking steps now, such as downsizing, which could help them avoid moving into care homes.

They are challenging the idea that it is better to “sit tight” in the family home.

The group also includes the heads of 13 charities and private companies providing housing for the elderly. They say it is “to the nation’s shame” that many older people are faced with a stark choice between spending their final years in institutions such as nursing homes, or struggling on in their family home, despite loneliness.

Polls have suggested that one person in five aged over 65 in Britain spends the day alone, and a quarter of over 75s spend a typical weekend without seeing or talking to anybody else.

There are 1.5 million people in Britain over the age of 85, a figure set to double in the next 20 years, and to reach five million by the middle of the century.

Less than 1 per cent of elderly people in the UK live in retirement villages or in housing designed to be easily adapted as people get older so they do not need to move.

Mr Burstow said that while people are “emotionally tied” to the homes they have lived in for many years, many might benefit in the long term from moving to somewhere adaptable while they are relatively young.

“It is a conversation that people need to have,” he said.


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Threat posed by resistance to antibiotics 'ranks alongside terrorism'

The problem is a “ticking time bomb” and should be put on the National Risk Register — which also includes “catastrophic terrorist attacks” and other civil emergencies, Prof Dame Sally Davies said.

Routine operations such as hip replacements could become fatal in just 20 years time if we lose the ability to fight infection, she said.

Dame Sally said the problem is “as important as climate change for the world” and urged the Government to raise the issue when meeting political leaders at the G8 summit in London in April.

In a report, Dame Sally also calls for better incentives for the pharmaceutical industry to develop new drugs.

The register sets out an assessment of the likelihood and potential impact of a range of different risks that may affect the UK. It is also designed to increase awareness about the types of threats and help government, individuals and organisations to think about their readiness.

Dame Sally’s report says: “Antimicrobial resistance is a ticking time bomb not only for the UK but also for the world.

“We need to work with everyone to ensure the apocalyptic scenario of widespread antimicrobial resistance does not become a reality.”

She added: “If we don’t act now, any one of us could go into hospital in 20 years for minor surgery and die because of an ordinary infection that can’t be treated by antibiotics.

“That’s why governments and organisations across the world, including the World Health Organisation and G8, need to take this seriously.”

The report also highlights the importance of better hygiene to avoid infections and of only prescribing antibiotics when needed.

The Department of Health said it is to publish the UK Antimicrobial Resistance Strategy setting out a five-year plan to address the issue.


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Sunday, 10 March 2013

oldenough2burmom: Everyone — after you’re done taking pictures...

Sit down and STFU. Your hypocrisy is showing.

This is to point out the hypocrisy of the people who should know better, but instead they choose to ignore what's right. If you can't understand how people would be FOR a health care system that discriminates based on pre-existing conditions. If you can't understand people who want less government but then want to legislate their religious beliefs to interfere with abortions and gay marriage. If you can't understand the ignorance behind those who say that global warming is a myth cuz they have snow where they live. If the fact that racism, sexism, misogyny and homophobia is still prevalent and still exists to this day blows your mind. If you don't understand why Michael Vick (rightfully so) went to jail for dog fighting, but it's ok for Sarah Palin to hunt on national TV. If people who throw their compostables and recyclables all in the garbage cuz they're too lazy piss you off. If you think that giving tax cuts to the richest 2% of America makes a total of ZERO economic sense. If you can't stand Fox News, the Westboro Baptist Church, National Organization for marriage and the following people: Glenn Beck, Rush Limbaugh, Bill O'Reilly, Ann Coulter, Sarah Palin, Christine O'Donnell, Rand Paul, Michelle Bachmann, Sharron Angle, Tucker Carlson, Maggie Gallagher, Brian Brown, Ken Buck, John Boehner, Pat Robertson, Shirley Phelps, Fred Phelps (and co.) and Michael Vick. If you love The Young Turks, MSNBC, Rachel Maddow and Keith Olbermann, Anthony Weiner and Bernie Frank. If you think Meghan McCain should consider becoming a democrat cuz she's just way too awesome to be a republican. If you think Glenn Beck should finally be off the air. If you think violent rhetoric does in fact influence people and should not be allowed on any side. If you think that Politicians should not be bought and should base their decisions on the over-all good of the citizens. If you just outright cannot understand the Republicans and why crazy unreasonable people still get a say in Politics, this place is for you. Although it's more like a stfuconservatives wanna be ;) LOL
I'm a Canadian with a passion for American politics, so I don't know everything about everything. Embarrassingly enough, I know more about American politics than I do my own, I'm working on it though.

-Chanty


View the original article here

Saturday, 9 March 2013

rock-it-ship: vile-insect: vicmorrowsghost: During his “We...

Sit down and STFU. Your hypocrisy is showing.

This is to point out the hypocrisy of the people who should know better, but instead they choose to ignore what's right. If you can't understand how people would be FOR a health care system that discriminates based on pre-existing conditions. If you can't understand people who want less government but then want to legislate their religious beliefs to interfere with abortions and gay marriage. If you can't understand the ignorance behind those who say that global warming is a myth cuz they have snow where they live. If the fact that racism, sexism, misogyny and homophobia is still prevalent and still exists to this day blows your mind. If you don't understand why Michael Vick (rightfully so) went to jail for dog fighting, but it's ok for Sarah Palin to hunt on national TV. If people who throw their compostables and recyclables all in the garbage cuz they're too lazy piss you off. If you think that giving tax cuts to the richest 2% of America makes a total of ZERO economic sense. If you can't stand Fox News, the Westboro Baptist Church, National Organization for marriage and the following people: Glenn Beck, Rush Limbaugh, Bill O'Reilly, Ann Coulter, Sarah Palin, Christine O'Donnell, Rand Paul, Michelle Bachmann, Sharron Angle, Tucker Carlson, Maggie Gallagher, Brian Brown, Ken Buck, John Boehner, Pat Robertson, Shirley Phelps, Fred Phelps (and co.) and Michael Vick. If you love The Young Turks, MSNBC, Rachel Maddow and Keith Olbermann, Anthony Weiner and Bernie Frank. If you think Meghan McCain should consider becoming a democrat cuz she's just way too awesome to be a republican. If you think Glenn Beck should finally be off the air. If you think violent rhetoric does in fact influence people and should not be allowed on any side. If you think that Politicians should not be bought and should base their decisions on the over-all good of the citizens. If you just outright cannot understand the Republicans and why crazy unreasonable people still get a say in Politics, this place is for you. Although it's more like a stfuconservatives wanna be ;) LOL
I'm a Canadian with a passion for American politics, so I don't know everything about everything. Embarrassingly enough, I know more about American politics than I do my own, I'm working on it though.

-Chanty


View the original article here

Friday, 8 March 2013

themindislimitless: badassmuslimahs: Emad Burnat and his wife...

Sit down and STFU. Your hypocrisy is showing.

This is to point out the hypocrisy of the people who should know better, but instead they choose to ignore what's right. If you can't understand how people would be FOR a health care system that discriminates based on pre-existing conditions. If you can't understand people who want less government but then want to legislate their religious beliefs to interfere with abortions and gay marriage. If you can't understand the ignorance behind those who say that global warming is a myth cuz they have snow where they live. If the fact that racism, sexism, misogyny and homophobia is still prevalent and still exists to this day blows your mind. If you don't understand why Michael Vick (rightfully so) went to jail for dog fighting, but it's ok for Sarah Palin to hunt on national TV. If people who throw their compostables and recyclables all in the garbage cuz they're too lazy piss you off. If you think that giving tax cuts to the richest 2% of America makes a total of ZERO economic sense. If you can't stand Fox News, the Westboro Baptist Church, National Organization for marriage and the following people: Glenn Beck, Rush Limbaugh, Bill O'Reilly, Ann Coulter, Sarah Palin, Christine O'Donnell, Rand Paul, Michelle Bachmann, Sharron Angle, Tucker Carlson, Maggie Gallagher, Brian Brown, Ken Buck, John Boehner, Pat Robertson, Shirley Phelps, Fred Phelps (and co.) and Michael Vick. If you love The Young Turks, MSNBC, Rachel Maddow and Keith Olbermann, Anthony Weiner and Bernie Frank. If you think Meghan McCain should consider becoming a democrat cuz she's just way too awesome to be a republican. If you think Glenn Beck should finally be off the air. If you think violent rhetoric does in fact influence people and should not be allowed on any side. If you think that Politicians should not be bought and should base their decisions on the over-all good of the citizens. If you just outright cannot understand the Republicans and why crazy unreasonable people still get a say in Politics, this place is for you. Although it's more like a stfuconservatives wanna be ;) LOL
I'm a Canadian with a passion for American politics, so I don't know everything about everything. Embarrassingly enough, I know more about American politics than I do my own, I'm working on it though.

-Chanty


View the original article here

How to dress: ruffles - video

Sorry, I could not read the content fromt this page.

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